• Inter-rater reliability of a national acute stroke register 

      Varmdal, Torunn; Ellekjær, Hanne; Fjærtoft, Hild; Indredavik, Bent; Lydersen, Stian; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-19)
      <p>Background: Medical quality registers are useful sources of knowledge about diseases and the health services. However, there are challenges in obtaining valid and reliable data. This study aims to assess the reliability in a national medical quality register. <p>Methods: We randomly selected 111 patients having had a stroke in 2012. An experienced stroke nurse completed the Norwegian Stroke ...
    • A meta-analysis of constraint-induced movement therapy after stroke 

      Thrane, Gyrd; Friborg, Oddgeir; Anke, Audny; Indredavik, Bent (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-09-02)
      <p><i>Objective - </i>To evaluate the effect of constraint-induced movement therapy in adult stroke patients and to examine the impact of time since stroke and various treatment modalities. <p><i>Data sources - </i>PubMed, EMBASE, Cochrane and PEDro trial registers were searched for clinical trials published before November 2012. <p><i>Study selection - </i>Randomized or quasi-randomized controlled ...
    • Safety and efficacy of tenecteplase in patients with wake-up stroke assessed by non-contrast CT (TWIST): a multicentre, open-label, randomised controlled trial. 

      Roaldsen, Melinda Berg; Eltoft, Agnethe; Wilsgaard, Tom; Christensen, Hanne; Engelter, Stefan T.; Indredavik, Bent; Jatužis, Dalius; Karelis, Guntis; Kõrv, Janika; Lundström, Erik; Petersson, Jesper; Putaala, Jukka; Søyland, Mary-Helen; Tveiten, Arnstein; Bivard, Andrew; Johnsen, Stein Harald; Mazya, Michael; Werring, David J; Wu, Teddy Y; de Marchis, Gian Marco; Robinson, Thompson G; Mathiesen, Ellisiv B (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-19)
      Background - Current evidence supports the use of intravenous thrombolysis with alteplase in patients with wake-up stroke selected with MRI or perfusion imaging and is recommended in clinical guidelines. However, access to advanced imaging techniques is often scarce. We aimed to determine whether thrombolytic treatment with intravenous tenecteplase given within 4·5 h of awakening improves functional ...
    • Statistical analysis plan for the randomized controlled trial Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST) 

      Eltoft, Agnethe; Wilsgaard, Tom; Roaldsen, Melinda Berg; Søyland, Mary-Helen; Lundström, Erik; Petersson, Jesper; Indredavik, Bent; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; De Marchis, Gian Marco; Werring, David J.; Robinson, Thompson; Tveiten, Arnstein; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-05-19)
      Background: Patients with wake-up ischemic stroke are frequently excluded from thrombolytic treatment due to unknown symptom onset time and limited availability of advanced imaging modalities. The Tenecteplase in Wake-up Ischaemic Stroke Trial (TWIST) is a randomized controlled trial of intravenous tenecteplase 0.25 mg/kg and standard care versus standard care alone (no thrombolysis) in patients ...
    • Tenecteplase in wake-up ischemic stroke trial: Protocol for a randomized-controlled trial 

      Roaldsen, Melinda Berg; Lindekleiv, Haakon; Eltoft, Agnethe; Jusufovic, Mirza; Søyland, Mary-Helen; Petersson, Jesper; Indredavik, Bent; Tveiten, Arnstein; Putaala, Jukka; Christensen, Hanne; Kõrv, Janika; Jatužis, Dalius; Engelter, Stefan T.; Marco De Marchis, Gian; Wilsgaard, Tom; Werring, David; Robinson, Thompson; Mathiesen, Ellisiv B.; Berge, Eivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-14)
      <p>Background: Patients with wake-up ischemic stroke who have evidence of salvageable tissue on advanced imaging can benefit from intravenous thrombolysis. It is not known whether patients who do not fulfil such imaging criteria might benefit from treatment, but studies indicate that treatment based on non-contrast CT criteria may be safe. Tenecteplase has shown promising results in patients with ...
    • Wake-up stroke and unknown-onset stroke; occurrence and characteristics from the nationwide Norwegian Stroke Register 

      Søyland, Mary-Helen; Tveiten, Arnstein; Eltoft, Agnethe; Øygarden, Halvor; Varmdal, Torunn; Indredavik, Bent; Mathiesen, Ellisiv B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06)
      Introduction: Population-based knowledge of the characteristics of wake-up stroke and unknown-onset stroke is limited. We compared occurrence and characteristics of ischaemic and haemorrhagic wake-up stroke, unknown-onset stroke and known-onset stroke in a nationwide register-based study. <p> <p>Patients and methods: We included patients registered in the Norwegian Stroke Register from 2012 through ...